Mouth Body Connection | Dental Practice Solutions

Optimal Oral Health and Its Role in Preventing Alzheimer’s Disease

By: Debbie Seidel-Bittke, RDH, BS

December 9, 2024

In recent years, a growing body of research has highlighted a surprising connection between oral health and brain health. As dental professionals, understanding the broader implications of oral hygiene can empower us to provide even greater value to our patients. One of the most concerning areas of the current research is the connection between oral inflammation and Alzheimer’s disease.

The Oral-Systemic Health Connection

The mouth is often referred to as the gateway to the body, and for good reason. It is home to millions of bacteria, some beneficial and some potentially harmful. Good oral hygiene practices, such as regular brushing, flossing, and preventive care, dental hygiene appointments help maintain a healthy balance of these bacteria. However, poor oral health can lead to gingivitis and periodontal disease, which has been linked to various systemic conditions, including cardiovascular disease, diabetes, and more recently, Alzheimer’s disease.

Understanding Alzheimer’s Disease

Alzheimer’s is a progressive neurological disorder characterized by memory loss, cognitive decline, and personality changes. It affects millions worldwide, posing significant challenges for patients, families, and healthcare systems. Alzheimer’s Disease is an inflammatory disease that occurs from the buildup of harmful proteins in the brain, such as amyloid-beta plaques. Amyloid-beta plaque and Tau Tangles are key factors when diagnosing Alzheimer’s Disease.

These same inflammatory proteins are also found in the oral cavity of patients who experience gingivitis and periodontitis.

The Link Between Oral Health and Alzheimer’s

Emerging research suggests that periodontal disease and poor oral health contribute to the development and progression of Alzheimer’s disease. The primary culprit of Alzheimer’s disease is believed to be inflammation. Chronic oral infections can lead to systemic inflammation, and this can accelerate the formation of amyloid plaques and neurofibrillary (Tau Tangles) tangles in the brain, a hallmark feature of Alzheimer’s Disease.

One bacterium in particular, Porphyromonas gingivalis, commonly associated with periodontal disease, has been found in the brains of Alzheimer’s patients. This bacterium can travel from the mouth to the brain, where it can contribute to inflammation which contributes to cognitive decline.

Importance of Preventive Dental Hygiene Appointments

Given this connection, preventive dental hygiene appointments are more crucial than ever. By maintaining optimal oral health, patients reduce inflammation in the mouth and lower the risk of systemic diseases, including Alzheimer’s Disease.

Here are some strategies to promote oral health and possibly protect brain health:

Routine Preventive Dental Hygiene Appointments: Encourage patients to schedule routine dental hygiene appointments at least twice a year for routine cleanings and examinations. Regular visits help detect and address oral health issues before they become a chronic disease. Patients who have a history of periodontal disease need to be seen for dental hygiene appointments more frequently. Dental professionals need to understand the benefits of photobiomodulation in prevention of inflammatory diseases. (See resources below #5 listed below to learn more about this.)
Daily Oral Hygiene: Educate patients on the importance of brushing twice a day and using dental floss or an interproximal oral hygiene aid to clean between the teeth every day.

Our message to patients: “Proper oral hygiene removes plaque and reduces the risk of gum disease. A healthy mouth leads to a longer and healthier life!”

3. Healthy Lifestyle Choices: Advise patients to adopt a balanced diet rich in fruits, vegetables, and whole grains, and to limit sugar intake. Sugar contributes to inflammation and inflammation contributes the the proteins that cause dementia. Additionally, discourage any type of tobacco use and excessive alcohol consumption, both which negatively impact oral and overall health. Exercise, aerobic – HIIT training – Level 2 exercise, and lifting weights also show promise to reduce cognitive decline. (See references below. #’s 6 & 7 to learn more about exercise and weight lifting.)

Managing Chronic Conditions: Encourage patients with diabetes, high blood pressure and high cholesterol, and other chronic systemic conditions, to manage their health proactively, as these conditions can exacerbate periodontal disease and inflammation, all which contribute to Alzheimer’s Disease.
Stay Informed: As dental professionals, staying updated on the latest research linking oral health and systemic diseases is vital. This knowledge enables us to educate patients effectively and advocate for our patients overall well-being.

Conclusion

While more research is needed to fully understand the relationship between oral inflammation and Alzheimer’s Disease. Current evidence underscores the importance of maintaining good oral hygiene and a healthy mouth. Dental professionals play a significant role in reducing oral inflammation and promoting overall health which can potentially lower our patients risk for Alzheimer’s Disease.

As we continue to explore the intricate connections between oral and systemic health, dental professionals are uniquely positioned to make a meaningful impact on our patients’ lives. Encouraging optimal oral health is not just about preserving smiles—it’s about contributing to long-lasting brain health and enhancing quality of our patients’ life for years to come.

Our job as dental professionals is to help patients live a longer and healthier life. This must be our message to patients in our dental world today!

For more information about this topic refer to the references below and plan to attend one of Debbie’s CE Courses during 2025. Email, or call us to book a course for your dental society, association or dental hygiene meeting.

References.

Porphyromonas Gingivalis and Alzheimer’s Disease. P. gingivalis in the brains of Alzheimer’s patients. Science Advances. Stephen S Dominy, et.al. 23 Jan 2019 Vol 5, Issue 1 DOI: 10.1126/sciadv.aau33.

2. How can Periodontitis or Periodontal Bacteria Influence Alzheimer’s Disease Features? A Systematic Review of Pre-Clinical Studies. J Alzheimers Disease. 2023 Nov 21;96(3):979–1010. doi 10.3233/JAD-230478.

3. Association between Tooth Loss and Cognitive Function among 3063 Chinese Older Adults: A Community-Based Study. PLOS ONE. 2015 Mar 24;10(3):e0120986. doi: 10.1371/journal.pone.0120986

4. Periodontal Health and Disease in the Context of Systemic Diseases. Mediators Inflamm. 2023 May 13;2023:9720947. doi: 10.1155/2023/9720947.

5. Therapeutic Potential of Photobiomodulation In Alzheimer’s Disease: A Systematic Review. J Lasers Med Sci. 2020 Dec 30;11(Suppl 1):S16–S22. doi: 10.34172/jlms.2020.S3.

6. Cognitive benefits from high intensity interval training may last for years. Medical News Today. Jessica Freeborn on July 23, 2024. Accessed on December 9, 2024.

7. The effects of resistance exercise on cognitive function, amyloidogenesis, and neuroinflammation in Alzheimer’s disease. Caroline Vieira Azevedo, et,al. Front Neurosci. 2023 Mar 2;17:1131214. doi: 10.3389/fnins.2023.1131214.

Oral Inflammation: A Journey Treating Disease to Total Health

By: Debbie Seidel-Bittke, RDH, BS

March 11, 2024

In the realm of healthcare, the mouth often serves as a gateway to understanding the broader state of one’s overall health. The journey from oral inflammation to total health is not merely about treating dental diseases; it’s about recognizing the interconnectedness between oral health and systemic well-being. In recent years, the scientific community has unearthed compelling evidence linking oral inflammation to a myriad of systemic conditions, underscoring the importance of holistic approaches in healthcare.

Oral inflammation, often manifested as gum disease (gingivitis and periodontitis), can be insidious. It begins as a seemingly innocuous condition characterized by swollen, bleeding gums but can escalate into a serious health threat if left unchecked. What many fail to realize is that oral inflammation is not confined to the mouth; it can serve as a precursor to more severe systemic diseases.

Research has demonstrated a clear association between oral inflammation and conditions such as cardiovascular disease, diabetes, respiratory infections, and even adverse pregnancy outcomes. The mechanisms underlying this relationship are complex but primarily revolve around the inflammatory nature of gum disease. Chronic inflammation in the oral cavity can trigger systemic inflammation, setting the stage for the development or exacerbation of various health issues.

Addressing oral inflammation entails more than routine dental care; it requires a paradigm shift towards a comprehensive approach to health and wellness. Dentists are increasingly adopting a holistic mindset, recognizing the interconnectedness between oral health and overall well-being. This shift is reflected in the emergence of integrative dental practices that prioritize preventive care, patient education, and collaboration with other healthcare professionals.

At the forefront of this movement is the recognition that oral health is not an isolated concern but an integral component of systemic health. Dental professionals are now delving deeper into the root causes of oral inflammation, exploring factors such as diet, lifestyle, genetics, and systemic health conditions. By understanding the underlying drivers of inflammation, clinicians can tailor treatment plans that address the root cause rather than merely managing symptoms.

Central to the journey from treating disease to achieving total health is the concept of personalized medicine. No two individuals are alike, and as such, their healthcare needs vary. Personalized oral health care involves a thorough assessment of each patient’s unique risk factors, health goals, and genetic predispositions. Leveraging advances in technology and diagnostics, allows clinicians to develop targeted interventions that optimize oral and systemic health outcomes.

Prevention lies at the heart of holistic oral healthcare. Empowering patients with knowledge and tools to maintain optimal oral hygiene and make informed lifestyle choices is paramount. From proper brushing and flossing techniques to mindful nutrition and stress management, patients play a proactive role in preserving their oral and systemic health.

In the pursuit of total health, collaboration among healthcare professionals is essential. Dentists, physicians, nutritionists, and other specialists must work together to address the multifaceted nature of health and disease. Integrated care models facilitate seamless communication and coordination, ensuring that patients receive comprehensive, evidence-based care that addresses their unique needs.

Beyond the confines of traditional healthcare settings, community engagement and education are instrumental in promoting oral health equity. Access to dental care remains a significant challenge for many underserved populations, exacerbating oral health disparities. By advocating for policies that prioritize preventive care and expand access to dental services, we can strive towards a future where oral health is a fundamental right for all.

In conclusion, the journey from treating oral inflammation to achieving total health is a multifaceted endeavor that transcends the boundaries of traditional healthcare. By adopting a holistic approach that addresses the root causes of inflammation, prioritizes prevention, embraces personalized medicine, and fosters collaboration, we can pave the way towards a healthier future for individuals and communities alike. Through collective effort and unwavering commitment, we can harness the transformative power of oral health to enrich lives and elevate overall well-being.

As we embark on this journey, let us not forget that oral health is not merely the absence of disease but a cornerstone of vitality and vitality and total health.

Check out our 7-Day Hygiene Department training which includes a webinar about Biologic Dentistry.

LEARN MORE HERE.